Description

Detailed view of Sibutramine DP

Sibutramine DP is a pharmaceutical product mainly used as an appetite suppressant for weight loss. Originally promoted as an obesity therapy, it was embraced in a number of other markets to tackle unmet needs-driven weight loss among patients who either had failed conventional diets and exercise or could not tolerate another medication.

Mechanism of Action

Sibutramine DP works by affecting certain neurochemicals in the brain: serotonin, norepinephrine and dopamine. Sibutramine blocks the reuptake of these neurotransmitters and thus keeps raising their levels at this place, increases satiety or decreases hunger. For people who binge or have difficulty feeling satisfied after a meal, this works quite well.

Clinical Use and Benefits

Sibutramine DP is recommended to be used in coordination with a reduced-calorie diet and exercise for the treatment of obesity, along with appropriate dietary changes and behavioral modification.

Safety and Side Effects

Although effective, Sibutramine DP are not without cardiovascular risks. Side effects: These may include dizziness, increased heart rate and blood pressure or dry mouth.

Legal and Market Status

The legal landing spot for Sibutramine DP has been a little more complicated. It was withdrawn in 2010 after the European Medicines Agency (EMA) and U.S. Food and Drug Administration (FDA) raised cardiovascular safety concerns about the drug, which is a prostanoid vasodilator that has been available for treatment of PAH since the mid-1990s. However, in a few countries it is available by prescription as part of controlled weight loss program.

Sibutramine DP is used alone or with other diet medications as a safe and effective way to manage obesity, because it will help them lose weight rapidly within months thus reduce the risk of many dangerous complications. Nevertheless, it needs to be adeptly controlled in order not to lead a few cardiovascular hazards. All patients should meet with a healthcare provider to understand the potential risks and benefits of any medication, including Sibutramine DP.